Biological & Soft Matter Seminar: Designing stimuli-responsive polymeric assemblies with high molecular precision (and introduction of the ADAMA Center)
Roey Amir, TAU
Zoom: https://tau-ac-il.zoom.us/j/88904888353?pwd=dDIwaXRxSjlsVElkR0dXdTNPTGhnZz09
Abstract:
Polymeric amphiphiles and their assemblies have been widely explored for applications ranging from controlled drug delivery to green chemistry. Over the last decade we developed dendritic amphiphiles, which we utilized as a modular toolbox for studying how small and precise changes in amphiphilicity and architecture affect the enzymatic responsiveness of polymeric assemblies. To allow us to track these assemblies in complex biological media we equip them with spectral response mechanism that allows them to report their enzymatic activation. In this talk, I will share our molecular understanding and future directions for tuning the functionality of micellar assemblies for applications ranging from controlled delivery to multi-components sensors and nanoreactors.
In addition, I will introduce the ADAMA Center for Novel Delivery Systems in Crop Protection, which was established 2 years ago in TAU, and offer great new tools for the characterization of soft-matter.